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Asclepiodotus (Greek Άσκληπιόδοτος) is a name borne by several figures from classical antiquity, including:
- Asclepiodotus of Heraclea: Macedonian commander of a contingent of Gauls in the Third Macedonian War of the 2nd century BC.
- Asclepiodotus (Stoic): A Greek Stoic philosopher of the 1st century BCE.
- Asclepiodotus of Lesbos: Ally of Mithridates VI of Pontus in his wars against the Romans in the 1st century BCE.
- Cassius Asclepiodotus: Bithynian nobleman with influence in the courts of the Roman emperors Nero and Galba.
- Julius Asclepiodotus: A Roman praetorian prefect who served under the emperors Aurelian, Probus and Diocletian and was consul in 292.
- Asclepiodotus of Alexandria: Pagan Greek Neoplatonist philosopher.
- Asclepiodotus (physician): A physician, mathematician and musician of the late 5th century AD, who was best known for promoting the medicinal uses of white hellebore.
- Flavius Asclepiodotus: Add brief definition or description